The Scinus Cell Expansion™ system enables clinical scale cell 3D cultivation in a controlled environment and provides a cost effective alternative to 2D cell growth in tissue culture flasks or cell stacks.
The system contains a single use bioreactor bag that can be used to cultivate adherent cells (e.g. human mesenchymal stem cells) to clinically relevant numbers of cells. It replaces at least 100 cell culture flasks per clinical production in a reproducible, controlled and efficient way.
Cells are grown on microcarriers in a single use, expandable bioreactor bag with continuous pH and dissolved oxygen control and biomass monitoring, which provides an optimized environment for growing cells. The closed system minimizes the risk of contamination. The Scinus can be operated by one technician from cell inoculation until harvest and with minimal time expenditure. Significantly less manpower is required compared to the traditional 2D expansion in T-flasks. The process requires up to 80% less medium than the 2D expansion.
Cells are grown on microcarriers in a single use, expandable bioreactor bag with continuous pH and dissolved oxygen control and biomass monitoring, which provides an optimized environment for growing cells. The closed system minimizes the risk of contamination. The Scinus can be operated by one technician from cell inoculation until harvest and with minimal time expenditure. Significantly less manpower is required compared to the traditional 2D expansion in T-flasks. The process requires up to 80% less medium than the 2D expansion.